Synthesis, Characterization and Biological Evaluation of Penicillin Derivatives Complexes with some Metal ions

number: 
3938
إنجليزية
department: 
Degree: 
Author: 
Yasser Hussam Sabah
year: 
2017

   Three new antibacterial ligands have been prepared in this work by the reaction of 6-amino penicillanic acid (6-APA) with terephthaladehyde, glyoxal and vanillin to produce L1, L2and L respectively.
     Nine new complexes have been prepared by the reaction of the above derivative ligands with  metal ions Co(II), Cu(II) and Zn (II), that L3 interacted with these metal ions in mole ratio [2:1], [2:1] and [1:1] metal to ligand [M:L] respectively. The synthesized compounds were characterized using IV11, LH-NMR for (L and L), Uv-Visible for all complexes and IR-spectroscopy, metal and elemental Micro analysis, conductivity and thermal analysis for (A21,B2 and C) The results suggested that the complexes could be with distorted octahedral geometry and the predicted formula of the new complexes were as follow: